Paris, France (Sports Network) - Roger Federer came from two-sets-to-love down to beat Juan Martin del Potro on Tuesday and reach the French Open semifinals for a seventh time.

The third-seeded former world No. 1 Federer outlasted the ninth-seeded del Potro 3-6, 6-7 (4-7), 6-2, 6-0, 6-3 on Court Lenglen.

The Swiss icon will meet the Novak Djokovic-Jo-Wilfried Tsonga winner in Friday's semifinals at Stade Roland Garros. The top-seeded Djokovic and fifth seed Tsonga are currently battling in the fifth set of their quarterfinal on Court Chatrier.

Federer appeared to be in a whole lot of trouble on Day 10 after dropping the first two sets against the former U.S. Open champion del Potro, but the Argentine saw his game take a turn for the worse after winning the second-set tiebreak.

Del Potro, who received some treatment for what appeared to be a left knee problem, was simply no match for Federer over the last three sets, as the Swiss great won 18-of-23 games to complete the comeback. Federer overcame a two-sets-to-love deficit for the seventh time in his amazing tennis career.

Federer prevailed in 3 hours, 24 minutes by striking 26 more winners (59-33) and tallying twice as many service breaks (8-4).

The 30-year-old Federer is now 12-2 lifetime against "Delpo," including wins in their last six encounters. The Swiss veteran is now 5-0 versus the towering Argentine this year, including victories in the Australian Open quarters and a final in Rotterdam.

Federer came from two-sets-to-one down to beat del Potro in a French Open semifinal in 2009, the same year the Argentine beat the Swiss in the U.S. Open final, which del Potro trailed two-sets-to-one before mounting a comeback in Flushing.

The sublime Federer will now appear in his 29th semifinal in his last 32 Grand Slam events. The 16-time major champ captured his lone French Open title in 2009 to complete a career Grand Slam and has been a four-time Roland Garros runner-up to Rafael Nadal, including last year in Paris.

Federer hasn't captured a major title since the 2010 Aussie Open.

The quarterfinals are scheduled to wrap up here on Wednesday when the second seed Nadal meets 12th-seeded fellow Spaniard Nicolas Almagro and fourth seed Andy Murray of Great Britain takes on sixth-seeded Spaniard David Ferrer. Nadal, Ferrer and Almagro each have yet to lose a set at this 2012 French fortnight.

The 10-time Grand Slam champion Nadal is a six-time French Open titlist, including wins in the previous two installments of the world's lone clay-court major.

The 2012 French Open champ will collect $1.5 million.

06/05 14:11:20 ET